STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GUCA2BGuanylate cyclase activator 2B. (92 aa)    
Predicted Functional Partners:
L5KMH5_PTEAL
Guanylate cyclase.
   
 
 0.741
GUCA2A
Guanylin.
   
  
 0.692
RAD17
Cell cycle checkpoint protein RAD17.
      
 0.589
NPR3
Atrial natriuretic peptide clearance receptor.
   
 
 0.579
FANCL
E3 ubiquitin-protein ligase FANCL.
      
 0.538
RAD18
E3 ubiquitin-protein ligase RAD18.
      
 0.536
MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2; Belongs to the protein kinase superfamily.
      
 0.517
CHAC1
Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
      
 0.454
EMD
Emerin.
      
 0.426
SLC39A5
Zinc transporter ZIP5.
      
 0.418
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.