node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APICC_00236 | APICC_01907 | A0A2A3ED48 | A0A2A3ELP7 | Kynurenine 3-monooxygenase. | UbiA prenyltransferase domain-containing protein. | 0.413 |
APICC_00236 | APICC_03379 | A0A2A3ED48 | A0A2A3EDB0 | Kynurenine 3-monooxygenase. | Chaperone activity of bc1 complex. | 0.524 |
APICC_00236 | APICC_08338 | A0A2A3ED48 | A0A2A3E8X7 | Kynurenine 3-monooxygenase. | AarF domain-containing protein kinase. | 0.524 |
APICC_00236 | coq2 | A0A2A3ED48 | A0A2A3EKN6 | Kynurenine 3-monooxygenase. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.907 |
APICC_00236 | coq5 | A0A2A3ED48 | A0A2A3EKW0 | Kynurenine 3-monooxygenase. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.851 |
APICC_00236 | coq6 | A0A2A3ED48 | A0A2A3E8X6 | Kynurenine 3-monooxygenase. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.524 |
APICC_00236 | coq7 | A0A2A3ED48 | A0A2A3ER32 | Kynurenine 3-monooxygenase. | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. | 0.840 |
APICC_00507 | APICC_01258 | A0A2A3E8I0 | A0A2A3ETN6 | Cell division cycle and apoptosis regulator protein. | F-box only protein. | 0.815 |
APICC_00507 | APICC_03749 | A0A2A3E8I0 | A0A2A3EA31 | Cell division cycle and apoptosis regulator protein. | Eukaryotic translation initiation factor. | 0.596 |
APICC_00507 | coq5 | A0A2A3E8I0 | A0A2A3EKW0 | Cell division cycle and apoptosis regulator protein. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.827 |
APICC_01258 | APICC_00507 | A0A2A3ETN6 | A0A2A3E8I0 | F-box only protein. | Cell division cycle and apoptosis regulator protein. | 0.815 |
APICC_01258 | APICC_01907 | A0A2A3ETN6 | A0A2A3ELP7 | F-box only protein. | UbiA prenyltransferase domain-containing protein. | 0.524 |
APICC_01258 | APICC_03749 | A0A2A3ETN6 | A0A2A3EA31 | F-box only protein. | Eukaryotic translation initiation factor. | 0.913 |
APICC_01258 | coq5 | A0A2A3ETN6 | A0A2A3EKW0 | F-box only protein. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.898 |
APICC_01907 | APICC_00236 | A0A2A3ELP7 | A0A2A3ED48 | UbiA prenyltransferase domain-containing protein. | Kynurenine 3-monooxygenase. | 0.413 |
APICC_01907 | APICC_01258 | A0A2A3ELP7 | A0A2A3ETN6 | UbiA prenyltransferase domain-containing protein. | F-box only protein. | 0.524 |
APICC_01907 | coq2 | A0A2A3ELP7 | A0A2A3EKN6 | UbiA prenyltransferase domain-containing protein. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.925 |
APICC_01907 | coq5 | A0A2A3ELP7 | A0A2A3EKW0 | UbiA prenyltransferase domain-containing protein. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.867 |
APICC_01907 | coq6 | A0A2A3ELP7 | A0A2A3E8X6 | UbiA prenyltransferase domain-containing protein. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.413 |
APICC_03379 | APICC_00236 | A0A2A3EDB0 | A0A2A3ED48 | Chaperone activity of bc1 complex. | Kynurenine 3-monooxygenase. | 0.524 |