A0A2Z6QZY0 protein (Rhizophagus clarus) - STRING interaction network

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second shell of interactors

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filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

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[Homology]

Score

A0A2Z6QZY0

Uncharacterized protein. (163 aa)

Predicted Functional Partners:

A0A2Z6QDU3

0.986

A0A2Z6R541

0.965

A0A2Z6SEU3

0.952

A0A2Z6R318

0.951

A0A2Z6SEA2

0.948

A0A2Z6RA97

0.947

A0A2Z6S2H8

0.947

A0A2Z6R835

0.938

A0A2Z6S0D8

0.936

LSM8

0.933

Your Current Organism:

Rhizophagus clarus

NCBI taxonomy Id: 94130
Other names: Glomus clarum, R. clarus, Rhizoglomus clarum, Rhizophagus clarus (T.H. Nicolson & N.C. Schenck) C. Walker & A. Schuessler 2010

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A2Z6QDU3	A0A2Z6QZY0	A0A2Z6QDU3	A0A2Z6QZY0	Uncharacterized protein.	Uncharacterized protein.	0.986
A0A2Z6QDU3	A0A2Z6R318	A0A2Z6QDU3	A0A2Z6R318	Uncharacterized protein.	Tr-type G domain-containing protein.	0.989
A0A2Z6QDU3	A0A2Z6R541	A0A2Z6QDU3	A0A2Z6R541	Uncharacterized protein.	Nop domain-containing protein.	0.997
A0A2Z6QDU3	A0A2Z6R835	A0A2Z6QDU3	A0A2Z6R835	Uncharacterized protein.	Sm domain-containing protein.	0.977
A0A2Z6QDU3	A0A2Z6RA97	A0A2Z6QDU3	A0A2Z6RA97	Uncharacterized protein.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.984
A0A2Z6QDU3	A0A2Z6S0D8	A0A2Z6QDU3	A0A2Z6S0D8	Uncharacterized protein.	Uncharacterized protein.	0.995
A0A2Z6QDU3	A0A2Z6S2H8	A0A2Z6QDU3	A0A2Z6S2H8	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D2.	0.985
A0A2Z6QDU3	A0A2Z6SEA2	A0A2Z6QDU3	A0A2Z6SEA2	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D3.	0.983
A0A2Z6QDU3	A0A2Z6SEU3	A0A2Z6QDU3	A0A2Z6SEU3	Uncharacterized protein.	Uncharacterized protein.	0.996
A0A2Z6QDU3	LSM8	A0A2Z6QDU3	A0A2Z6Q929	Uncharacterized protein.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.996
A0A2Z6QZY0	A0A2Z6QDU3	A0A2Z6QZY0	A0A2Z6QDU3	Uncharacterized protein.	Uncharacterized protein.	0.986
A0A2Z6QZY0	A0A2Z6R318	A0A2Z6QZY0	A0A2Z6R318	Uncharacterized protein.	Tr-type G domain-containing protein.	0.951
A0A2Z6QZY0	A0A2Z6R541	A0A2Z6QZY0	A0A2Z6R541	Uncharacterized protein.	Nop domain-containing protein.	0.965
A0A2Z6QZY0	A0A2Z6R835	A0A2Z6QZY0	A0A2Z6R835	Uncharacterized protein.	Sm domain-containing protein.	0.938
A0A2Z6QZY0	A0A2Z6RA97	A0A2Z6QZY0	A0A2Z6RA97	Uncharacterized protein.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.947
A0A2Z6QZY0	A0A2Z6S0D8	A0A2Z6QZY0	A0A2Z6S0D8	Uncharacterized protein.	Uncharacterized protein.	0.936
A0A2Z6QZY0	A0A2Z6S2H8	A0A2Z6QZY0	A0A2Z6S2H8	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D2.	0.947
A0A2Z6QZY0	A0A2Z6SEA2	A0A2Z6QZY0	A0A2Z6SEA2	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D3.	0.948
A0A2Z6QZY0	A0A2Z6SEU3	A0A2Z6QZY0	A0A2Z6SEU3	Uncharacterized protein.	Uncharacterized protein.	0.952
A0A2Z6QZY0	LSM8	A0A2Z6QZY0	A0A2Z6Q929	Uncharacterized protein.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.933

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Network Stats

number of nodes:

11

number of edges:

22

average node degree:

4

avg. local clustering coefficient:

0.781

expected number of edges:

11

PPI enrichment p-value:

0.00219

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009167

Purine ribonucleoside monophosphate metabolic process

5 of 11

1.93

2.86

4.00e-07

GO:0009150

Purine ribonucleotide metabolic process

8 of 49

1.49

2.33

2.79e-08

GO:0009165

Nucleotide biosynthetic process

8 of 60

1.4

2.12

2.79e-08

GO:0009132

Nucleoside diphosphate metabolic process

4 of 14

1.73

1.95

3.70e-05

GO:0046037

GMP metabolic process

3 of 5

2.05

1.92

0.00015

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019205

Nucleobase-containing compound kinase activity

3 of 11

1.71

0.97

0.0112

GO:0004748

Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor

2 of 2

2.27

0.93

0.0189

GO:0004385

Guanylate kinase activity

2 of 2

2.27

0.93

0.0189

GO:0106130

Purine phosphoribosyltransferase activity

2 of 4

1.97

0.91

0.0189

GO:0016776

Phosphotransferase activity, phosphate group as acceptor

3 of 15

1.57

0.89

0.0144

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005971

Ribonucleoside-diphosphate reductase complex

2 of 2

2.27

0.98

0.0153

GO:0005737

Cytoplasm

10 of 713

0.42

0.31

0.0153

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:673

Mixed, incl. Purine nucleoside monophosphate metabolic process, and Ribonucleoside hydrolase-like

7 of 21

1.8

3.37

1.38e-09

CL:676

Purine nucleoside monophosphate metabolic process, and Ribonucleoside hydrolase-like

6 of 14

1.9

3.33

1.26e-08

CL:671

Mixed, incl. Nucleoside monophosphate metabolic process, and Pteridine-containing compound metabolic process

9 of 40

1.62

3.24

2.71e-11

CL:678

Purine nucleoside monophosphate biosynthetic process

2 of 6

1.8

0.69

0.0475

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

11 of 72

1.46

2.97

2.17e-14

map00240

Pyrimidine metabolism

3 of 43

1.12

0.55

0.0489

map01100

Metabolic pathways

11 of 614

0.53

0.46

8.76e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-168249

Innate Immune System

3 of 19

1.47

1.05

0.0042

MAP-168256

Immune System

3 of 24

1.37

1.0

0.0042

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005971

Ribonucleoside-diphosphate reductase complex

2 of 2

2.27

0.82

0.0314

GOCC:0005622

Intracellular

10 of 759

0.39

0.28

0.0362

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0328

Glycosyltransferase

3 of 11

1.71

1.08

0.0063

KW-0660

Purine salvage

2 of 3

2.1

0.9

0.0205

KW-0808

Transferase

6 of 223

0.7

0.43

0.0264

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR029057

Phosphoribosyltransferase-like

3 of 10

1.75

0.81

0.0266

IPR000836

Phosphoribosyltransferase domain

3 of 10

1.75

0.81

0.0266

IPR008145

Guanylate kinase/L-type calcium channel beta subunit

2 of 2

2.27

0.74

0.0438

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00072

Guanylate kinase homologues.

2 of 2

2.27

1.04

0.0116

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