node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A2Z6Q728 | A0A2Z6Q8V4 | A0A2Z6Q728 | A0A2Z6Q8V4 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.997 |
A0A2Z6Q728 | A0A2Z6QJH0 | A0A2Z6Q728 | A0A2Z6QJH0 | DNA helicase; Belongs to the MCM family. | Sld5 domain-containing protein. | 0.994 |
A0A2Z6Q728 | A0A2Z6QT51 | A0A2Z6Q728 | A0A2Z6QT51 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
A0A2Z6Q728 | A0A2Z6QWV0 | A0A2Z6Q728 | A0A2Z6QWV0 | DNA helicase; Belongs to the MCM family. | Uncharacterized protein. | 0.996 |
A0A2Z6Q728 | A0A2Z6QWY5 | A0A2Z6Q728 | A0A2Z6QWY5 | DNA helicase; Belongs to the MCM family. | Uncharacterized protein. | 0.998 |
A0A2Z6Q728 | A0A2Z6RWZ0 | A0A2Z6Q728 | A0A2Z6RWZ0 | DNA helicase; Belongs to the MCM family. | DNA helicase. | 0.999 |
A0A2Z6Q728 | A0A2Z6S687 | A0A2Z6Q728 | A0A2Z6S687 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
A0A2Z6Q728 | A0A2Z6SNB3 | A0A2Z6Q728 | A0A2Z6SNB3 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
A0A2Z6Q728 | A0A2Z6SQZ9 | A0A2Z6Q728 | A0A2Z6SQZ9 | DNA helicase; Belongs to the MCM family. | CDT1_C domain-containing protein. | 0.999 |
A0A2Z6Q728 | MCM7 | A0A2Z6Q728 | A0A2Z6R8Q8 | DNA helicase; Belongs to the MCM family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
A0A2Z6Q8V4 | A0A2Z6Q728 | A0A2Z6Q8V4 | A0A2Z6Q728 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | DNA helicase; Belongs to the MCM family. | 0.997 |
A0A2Z6Q8V4 | A0A2Z6QT51 | A0A2Z6Q8V4 | A0A2Z6QT51 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | DNA helicase; Belongs to the MCM family. | 0.996 |
A0A2Z6Q8V4 | A0A2Z6QWY5 | A0A2Z6Q8V4 | A0A2Z6QWY5 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | Uncharacterized protein. | 0.986 |
A0A2Z6Q8V4 | A0A2Z6RWZ0 | A0A2Z6Q8V4 | A0A2Z6RWZ0 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | DNA helicase. | 0.998 |
A0A2Z6Q8V4 | A0A2Z6S687 | A0A2Z6Q8V4 | A0A2Z6S687 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | DNA helicase; Belongs to the MCM family. | 0.998 |
A0A2Z6Q8V4 | A0A2Z6SNB3 | A0A2Z6Q8V4 | A0A2Z6SNB3 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | DNA helicase; Belongs to the MCM family. | 0.997 |
A0A2Z6Q8V4 | A0A2Z6SQZ9 | A0A2Z6Q8V4 | A0A2Z6SQZ9 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | CDT1_C domain-containing protein. | 0.999 |
A0A2Z6Q8V4 | MCM7 | A0A2Z6Q8V4 | A0A2Z6R8Q8 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.996 |
A0A2Z6QJH0 | A0A2Z6Q728 | A0A2Z6QJH0 | A0A2Z6Q728 | Sld5 domain-containing protein. | DNA helicase; Belongs to the MCM family. | 0.994 |
A0A2Z6QJH0 | A0A2Z6QT51 | A0A2Z6QJH0 | A0A2Z6QT51 | Sld5 domain-containing protein. | DNA helicase; Belongs to the MCM family. | 0.992 |