node1 | node2 | node1 annotation | node2 annotation | score |
A0A2Z6QE72 | A0A2Z6RFU3 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. | 0.500 |
A0A2Z6QHC2 | A0A2Z6RFU3 | Uncharacterized protein. | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. | 0.457 |
A0A2Z6R9A2 | A0A2Z6RFU3 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. | 0.465 |
A0A2Z6R9A2 | A0A2Z6RLM9 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.508 |
A0A2Z6R9A2 | A0A2Z6RMR2 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | 0.991 |
A0A2Z6RFU3 | A0A2Z6QE72 | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.500 |
A0A2Z6RFU3 | A0A2Z6QHC2 | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. | Uncharacterized protein. | 0.457 |
A0A2Z6RFU3 | A0A2Z6R9A2 | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.465 |
A0A2Z6RFU3 | A0A2Z6RLM9 | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. | 5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.457 |
A0A2Z6RFU3 | A0A2Z6RMR2 | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | 0.457 |
A0A2Z6RFU3 | A0A2Z6SHB8 | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. | GHMP_kinases_N domain-containing protein. | 0.414 |
A0A2Z6RLM9 | A0A2Z6R9A2 | 5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.508 |
A0A2Z6RLM9 | A0A2Z6RFU3 | 5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. | 0.457 |
A0A2Z6RLM9 | A0A2Z6RMR2 | 5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | 0.509 |
A0A2Z6RMR2 | A0A2Z6R9A2 | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.991 |
A0A2Z6RMR2 | A0A2Z6RFU3 | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. | 0.457 |
A0A2Z6RMR2 | A0A2Z6RLM9 | Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. | 5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.509 |
A0A2Z6SHB8 | A0A2Z6RFU3 | GHMP_kinases_N domain-containing protein. | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. | 0.414 |