STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2Z6RJ31ERCC4 domain-containing protein. (986 aa)    
Predicted Functional Partners:
A0A2Z6R150
Uncharacterized protein.
   
 0.999
A0A2Z6R553
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.988
A0A2Z6Q4F3
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.983
A0A2Z6RM93
XPA_C domain-containing protein.
    
 0.983
A0A2Z6RHZ1
RING-type domain-containing protein.
    
 0.981
A0A2Z6Q877
DUF1767 domain-containing protein.
    
 0.972
A0A2Z6S1D1
ERCC4 domain-containing protein.
    
 0.959
A0A2Z6RSS5
Uncharacterized protein.
   
 0.954
A0A2Z6SEU4
Uncharacterized protein.
   
 0.951
A0A2Z6QMZ7
Uncharacterized protein.
    
 0.930
Your Current Organism:
Rhizophagus clarus
NCBI taxonomy Id: 94130
Other names: Glomus clarum, R. clarus, Rhizoglomus clarum, Rhizophagus clarus (T.H. Nicolson & N.C. Schenck) C. Walker & A. Schuessler 2010
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.