STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TPAR_05755Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (498 aa)    
Predicted Functional Partners:
TPAR_04540
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.954
TPAR_03493
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]
     
 0.846
TPAR_03494
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase.
     
 0.846
TPAR_04288
BPP domain-containing protein.
    
  0.767
TPAR_03778
Nucleoporin GLE1.
    
 
 0.671
TPAR_04622
2-oxoisovalerate dehydrogenase beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 0.664
TPAR_05898
Ribose-phosphate pyrophosphokinase 5.
   
 0.563
TPAR_05538
Ribose-phosphate pyrophosphokinase 3.
   
 0.563
TPAR_01819
Ribose-phosphate pyrophosphokinase 1.
   
 0.562
TPAR_02683
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.561
Your Current Organism:
Tolypocladium paradoxum
NCBI taxonomy Id: 94208
Other names: Cordyceps paradoxa, Elaphocordyceps paradoxa, T. paradoxum, Tolypocladium paradoxum (Kobayasi) Quandt, Kepler & Spatafora, 2014
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.