STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
luxSS-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (161 aa)    
Predicted Functional Partners:
KRO09627.1
Methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
 
 
 0.993
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
    
 0.970
KRO14498.1
Hypothetical protein.
 
  
 0.958
KRO11733.1
Methylenetetrahydrofolate reductase.
    
 0.957
KRO07654.1
O-succinylhomoserine (thiol)-lyase.
  
 
 0.952
KRO12531.1
metH protein.
 
  
 0.945
KRO09204.1
Homoserine dehydrogenase.
    
 0.810
KRO07586.1
Homoserine dehydrogenase.
    
 0.810
KRO08084.1
Aminotransferase.
    
  0.798
KRO10476.1
Aminotransferase.
    
  0.798
Your Current Organism:
Lactobacillus xiangfangensis
NCBI taxonomy Id: 942150
Other names: L. xiangfangensis, LMG 26013, LMG:26013, Lactobacillus sp. 3.1.1, Lactobacillus xiangfangensis Gu et al. 2012, NBRC 108914, NCIMB 14687, strain 3.1.1
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