STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribAGtp cyclohydrolase ii; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. (402 aa)    
Predicted Functional Partners:
ribH
Riboflavin synthase, beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.999
KRO11642.1
Riboflavin synthase, alpha subunit.
 0.999
KRO11643.1
Pyrimidine reductase, riboflavin biosynthesis; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 0.999
KRO10882.1
Nucleoside-diphosphate kinase; Belongs to the NDK family.
  
 0.974
KRO14486.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase.
  
 
 0.946
tadA
Cytosine adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
    
 0.941
KRO08677.1
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.941
folE
GTP cyclohydrolase I.
  
 
 0.941
KRO10902.1
Hypothetical protein.
   
    0.934
KRO08632.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.930
Your Current Organism:
Lactobacillus xiangfangensis
NCBI taxonomy Id: 942150
Other names: L. xiangfangensis, LMG 26013, LMG:26013, Lactobacillus sp. 3.1.1, Lactobacillus xiangfangensis Gu et al. 2012, NBRC 108914, NCIMB 14687, strain 3.1.1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.