Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSMMOP00000001337Zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila). (445 aa)    
Predicted Functional Partners:
ENSMMOP00000028078
POU domain protein.
    
 0.763
ENSMMOP00000013394
Phosphoribosylglycinamide formyltransferase.
     
  0.649
ENSMMOP00000001851
SRY-box transcription factor 2.
   
 0.609
ENSMMOP00000002399
SRY-box transcription factor 3.
   
 0.609
ENSMMOP00000004121
Myb-like, SWIRM and MPN domains 1.
   
  0.596
ENSMMOP00000004803
NDK domain-containing protein.
    
 0.579
ENSMMOP00000002015
Forkhead box D3.
    
 0.578
ENSMMOP00000007502
Receptor-interacting serine-threonine kinase 4.
    
 0.574
ENSMMOP00000021055
Uncharacterized protein.
    
  0.574
ENSMMOP00000023352
V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]
   
 
 0.573
Your Current Organism:
Mola mola
NCBI taxonomy Id: 94237
Other names: M. mola, ocean sunfish
Server load: low (8%) [HD]