Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSMMOP00000001348Aldo_ket_red domain-containing protein. (326 aa)    
Predicted Functional Partners:
ENSMMOP00000001254
3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
     
 0.914
ENSMMOP00000028037
3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
     
 0.914
ENSMMOP00000003885
Hydroxysteroid (11-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.905
ENSMMOP00000007258
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 
 0.894
ENSMMOP00000000983
Cytochrome P450, family 21, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family.
     
 0.893
ENSMMOP00000013332
Hydroxysteroid (17-beta) dehydrogenase 8.
  
 0.892
ENSMMOP00000022476
UDP glucuronosyltransferase 1 family, polypeptide B5; Belongs to the UDP-glycosyltransferase family.
   
 
 0.886
ENSMMOP00000008483
Steroid 5 alpha-reductase 3.
   
 
 0.883
ENSMMOP00000000695
Hydroxysteroid (11-beta) dehydrogenase 1-like a.
  
  0.882
ENSMMOP00000022523
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; Belongs to the 3-beta-HSD family.
    
 0.882
Your Current Organism:
Mola mola
NCBI taxonomy Id: 94237
Other names: M. mola, ocean sunfish
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