Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSMMOP00000001378Uncharacterized protein. (160 aa)    
Predicted Functional Partners:
ENSMMOP00000010429
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.994
ENSMMOP00000016143
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.991
ENSMMOP00000000786
Growth arrest-specific 7a.
    
 0.987
ENSMMOP00000027372
Growth arrest specific 7.
    
 0.987
ENSMMOP00000018988
Synergin, gamma.
   
 0.968
ENSMMOP00000008585
Centrosomal protein 135.
    
 0.967
ENSMMOP00000010928
Epidermal growth factor receptor pathway substrate 15-like 1a.
    
 0.967
ENSMMOP00000019495
AP complex subunit beta.
    
 0.967
ENSMMOP00000022847
Adaptor related protein complex 4 subunit beta 1.
    
 0.967
ENSMMOP00000023075
AP complex subunit beta.
    
 0.967
Your Current Organism:
Mola mola
NCBI taxonomy Id: 94237
Other names: M. mola, ocean sunfish
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