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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSMMOP00000001432MutL_C domain-containing protein. (412 aa)    
Predicted Functional Partners:
ENSMMOP00000011029
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).
    
 0.997
ENSMMOP00000000794
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 0.968
ENSMMOP00000017885
MutS homolog 2 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR).
  
 0.968
ENSMMOP00000004295
MutS homolog 5.
  
 0.952
ENSMMOP00000004402
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 0.952
ENSMMOP00000017014
MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR).
  
 0.952
ENSMMOP00000023271
Vesicle (multivesicular body) trafficking 1.
    
   0.916
ENSMMOP00000017045
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.888
ENSMMOP00000016819
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
   
 0.875
ENSMMOP00000009327
Exonuclease 1.
  
 0.869
Your Current Organism:
Mola mola
NCBI taxonomy Id: 94237
Other names: M. mola, ocean sunfish
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