STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNAH11Dynein, axonemal, heavy chain 11. (4425 aa)    
Predicted Functional Partners:
ENSMMOP00000009655
Dynactin 2 (p50).
    
 0.850
PAFAH1B1-2
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
    
 0.826
PAFAH1B1
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
    
 0.826
ENSMMOP00000018669
Dynactin 1a.
   
 0.812
ENSMMOP00000028286
Dynactin 1b.
   
 0.812
ENSMMOP00000010156
Dynein, cytoplasmic 2, light intermediate chain 1.
    
 0.795
ENSMMOP00000002467
Dynein, cytoplasmic 1, intermediate chain 2a.
   
 0.779
ENSMMOP00000010437
Dynein, cytoplasmic 1, intermediate chain 2b.
   
 0.779
DYNC1I1
Dynein cytoplasmic 1 intermediate chain 1.
   
 0.779
ENSMMOP00000016909
Dynein light chain.
    
 0.774
Your Current Organism:
Mola mola
NCBI taxonomy Id: 94237
Other names: M. mola, ocean sunfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.