close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSMMOP00000001587FYVE, RhoGEF and PH domain containing 5a. (1141 aa)    
Predicted Functional Partners:
ENSMMOP00000016147
RAB4B, member RAS oncogene family.
    
 0.604
ENSMMOP00000020117
RAB4a, member RAS oncogene family.
    
 0.604
ENSMMOP00000004273
Mitochondrial calcium uptake 1.
   
 0.594
ENSMMOP00000007640
Mitochondrial calcium uptake 2.
   
 0.594
ENSMMOP00000016890
Phosphatidylinositol 3-kinase catalytic subunit type 3.
     
 0.557
PTK7
Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.519
ENSMMOP00000011261
RAB9B, member RAS oncogene family.
     
 0.518
ENSMMOP00000016196
Uncharacterized protein.
     
 0.518
ENSMMOP00000022648
Armadillo repeat containing 5.
     
 0.518
RAB9A
RAB9A, member RAS oncogene family.
     
 0.518
Your Current Organism:
Mola mola
NCBI taxonomy Id: 94237
Other names: M. mola, ocean sunfish
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.