Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSMMOP00000001697Excision repair cross-complementation group 6-like 2. (1156 aa)    
Predicted Functional Partners:
ENSMMOP00000017045
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.953
ENSMMOP00000013309
Uncharacterized protein.
  
 0.928
ENSMMOP00000004243
RAD54 homolog B.
  
0.920
ENSMMOP00000028879
RAD18 E3 ubiquitin protein ligase.
   
 0.878
ENSMMOP00000025779
Actin-like 6A; Belongs to the actin family.
    
 0.877
ENSMMOP00000009327
Exonuclease 1.
  
 0.843
ENSMMOP00000028919
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 0.837
ENSMMOP00000025853
DNA methyltransferase 1 associated protein 1.
    
 0.835
ENSMMOP00000017129
RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae).
    
 
 0.834
ENSMMOP00000003311
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 
 0.818
Your Current Organism:
Mola mola
NCBI taxonomy Id: 94237
Other names: M. mola, ocean sunfish
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