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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSMMOP00000001931Matrix metallopeptidase 25b. (559 aa)    
Predicted Functional Partners:
ENSMMOP00000012063
Ubiquitin-conjugating enzyme E2 variant 1.
   
 
  0.812
ENSMMOP00000014325
TIMP metallopeptidase inhibitor 2b.
    
 0.785
ENSMMOP00000017243
TIMP metallopeptidase inhibitor 2a.
    
 0.785
TIMP3
TIMP metallopeptidase inhibitor 3.
    
 0.781
ENSMMOP00000013971
TIMP metallopeptidase inhibitor 4, tandem duplicate 1.
    
 0.703
ENSMMOP00000011799
Heparin-binding EGF-like growth factor a.
    
 0.652
ENSMMOP00000007611
ZnMc domain-containing protein.
  
0.627
MMP1
Matrix metallopeptidase 1.
  
0.625
ENSMMOP00000006824
Matrix metallopeptidase 13b.
  
0.621
ENSMMOP00000021614
Matrix metallopeptidase 2.
   
0.590
Your Current Organism:
Mola mola
NCBI taxonomy Id: 94237
Other names: M. mola, ocean sunfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.