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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSMMOP00000001985Sorting nexin 10b. (211 aa)    
Predicted Functional Partners:
ENSMMOP00000020394
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.947
ENSMMOP00000018843
Sorting nexin 15.
     
 0.867
ENSMMOP00000007813
Uncharacterized protein.
    
 0.841
ENSMMOP00000018538
VPS26, retromer complex component B.
    
 0.841
ENSMMOP00000020927
VPS26, retromer complex component A.
    
 0.841
ENSMMOP00000019462
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 0.833
ENSMMOP00000020914
Ribosomal protein S6 kinase polypeptide 1.
     
 0.822
ENSMMOP00000007958
Wnt ligand secretion mediator.
    
 0.745
ENSMMOP00000021754
Ubiquitin carboxyl-terminal hydrolase.
    
 0.686
ENSMMOP00000001727
Sorting nexin 22.
     
 0.600
Your Current Organism:
Mola mola
NCBI taxonomy Id: 94237
Other names: M. mola, ocean sunfish
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