ENSMMOP00000006490 protein (Mola mola) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ENSMMOP00000006490

PRP39 pre-mRNA processing factor 39 homolog (yeast). (614 aa)

Predicted Functional Partners:

SNRPC

0.934

ENSMMOP00000020313

0.933

ENSMMOP00000016675

0.924

ENSMMOP00000008819

0.919

ENSMMOP00000015866

0.915

ENSMMOP00000028491

0.915

ENSMMOP00000025134

0.910

ENSMMOP00000009206

0.901

ENSMMOP00000005346

0.897

SART1

0.883

Your Current Organism:

Mola mola

NCBI taxonomy Id: 94237
Other names: M. mola, ocean sunfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMMOP00000005346	ENSMMOP00000006490	ENSMMOP00000005346	ENSMMOP00000006490	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	PRP39 pre-mRNA processing factor 39 homolog (yeast).	0.897
ENSMMOP00000005346	ENSMMOP00000008819	ENSMMOP00000005346	ENSMMOP00000008819	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	CDC5 cell division cycle 5-like (S. pombe).	0.975
ENSMMOP00000005346	ENSMMOP00000009206	ENSMMOP00000005346	ENSMMOP00000009206	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	Small nuclear ribonucleoprotein polypeptide F.	0.997
ENSMMOP00000005346	ENSMMOP00000015866	ENSMMOP00000005346	ENSMMOP00000015866	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	tRNA selenocysteine 1 associated protein 1a.	0.938
ENSMMOP00000005346	ENSMMOP00000016675	ENSMMOP00000005346	ENSMMOP00000016675	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	N(alpha)-acetyltransferase 38, NatC auxiliary subunit.	0.989
ENSMMOP00000005346	ENSMMOP00000020313	ENSMMOP00000005346	ENSMMOP00000020313	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	Small nuclear ribonucleoprotein polypeptide A.	0.994
ENSMMOP00000005346	ENSMMOP00000025134	ENSMMOP00000005346	ENSMMOP00000025134	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.991
ENSMMOP00000005346	ENSMMOP00000028491	ENSMMOP00000005346	ENSMMOP00000028491	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	tRNA selenocysteine 1 associated protein 1b.	0.938
ENSMMOP00000005346	SART1	ENSMMOP00000005346	ENSMMOP00000005035	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP.	0.877
ENSMMOP00000005346	SNRPC	ENSMMOP00000005346	ENSMMOP00000017267	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]	0.992
ENSMMOP00000006490	ENSMMOP00000005346	ENSMMOP00000006490	ENSMMOP00000005346	PRP39 pre-mRNA processing factor 39 homolog (yeast).	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.897
ENSMMOP00000006490	ENSMMOP00000008819	ENSMMOP00000006490	ENSMMOP00000008819	PRP39 pre-mRNA processing factor 39 homolog (yeast).	CDC5 cell division cycle 5-like (S. pombe).	0.919
ENSMMOP00000006490	ENSMMOP00000009206	ENSMMOP00000006490	ENSMMOP00000009206	PRP39 pre-mRNA processing factor 39 homolog (yeast).	Small nuclear ribonucleoprotein polypeptide F.	0.901
ENSMMOP00000006490	ENSMMOP00000015866	ENSMMOP00000006490	ENSMMOP00000015866	PRP39 pre-mRNA processing factor 39 homolog (yeast).	tRNA selenocysteine 1 associated protein 1a.	0.915
ENSMMOP00000006490	ENSMMOP00000016675	ENSMMOP00000006490	ENSMMOP00000016675	PRP39 pre-mRNA processing factor 39 homolog (yeast).	N(alpha)-acetyltransferase 38, NatC auxiliary subunit.	0.924
ENSMMOP00000006490	ENSMMOP00000020313	ENSMMOP00000006490	ENSMMOP00000020313	PRP39 pre-mRNA processing factor 39 homolog (yeast).	Small nuclear ribonucleoprotein polypeptide A.	0.933
ENSMMOP00000006490	ENSMMOP00000025134	ENSMMOP00000006490	ENSMMOP00000025134	PRP39 pre-mRNA processing factor 39 homolog (yeast).	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.910
ENSMMOP00000006490	ENSMMOP00000028491	ENSMMOP00000006490	ENSMMOP00000028491	PRP39 pre-mRNA processing factor 39 homolog (yeast).	tRNA selenocysteine 1 associated protein 1b.	0.915
ENSMMOP00000006490	SART1	ENSMMOP00000006490	ENSMMOP00000005035	PRP39 pre-mRNA processing factor 39 homolog (yeast).	Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP.	0.883
ENSMMOP00000006490	SNRPC	ENSMMOP00000006490	ENSMMOP00000017267	PRP39 pre-mRNA processing factor 39 homolog (yeast).	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]	0.934