STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSMMOP00000012906Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)    
Predicted Functional Partners:
FGFR1
Fibroblast growth factor receptor.
    
 0.947
ENSMMOP00000014138
Fibroblast growth factor receptor 1b.
    
 0.930
ENSMMOP00000011259
Fibroblast growth factor receptor.
    
 0.929
ENSMMOP00000019538
Fibroblast growth factor receptor.
    
 0.911
ENSMMOP00000028189
Fibroblast growth factor receptor.
    
 0.911
ENSMMOP00000008264
Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.
   
 0.885
ENSMMOP00000003945
Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.881
ENSMMOP00000003949
Colony stimulating factor 1 receptor, a; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.881
ENSMMOP00000008389
Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.881
ENSMMOP00000010709
KIT proto-oncogene, receptor tyrosine kinase b.
    
 0.881
Your Current Organism:
Mola mola
NCBI taxonomy Id: 94237
Other names: M. mola, ocean sunfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.