STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSMMOP00000015425Growth factor independent 1B transcription repressor. (328 aa)    
Predicted Functional Partners:
ENSMMOP00000013157
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
 0.671
ENSMMOP00000024875
Lamin B1; Belongs to the intermediate filament family.
    
 
 0.665
ENSMMOP00000011372
ANK_REP_REGION domain-containing protein.
    
  0.640
ENSMMOP00000014082
BRCT domain-containing protein.
    
  0.640
ENSMMOP00000013948
Suppressor of fused homolog.
    
  0.627
ENSMMOP00000021055
Uncharacterized protein.
    
  0.622
ENSMMOP00000002908
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
   
 0.618
ENSMMOP00000007502
Receptor-interacting serine-threonine kinase 4.
    
 0.614
ENSMMOP00000011174
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
  0.613
ENSMMOP00000027408
Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily.
    
  0.613
Your Current Organism:
Mola mola
NCBI taxonomy Id: 94237
Other names: M. mola, ocean sunfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.