STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSMMOP00000017675Kelch domain containing 7A. (633 aa)    
Predicted Functional Partners:
ENSMMOP00000010990
CDK2 associated cullin domain 1; Belongs to the cullin family.
    
 0.565
ENSMMOP00000013419
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.565
ENSMMOP00000020003
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.565
ENSMMOP00000021247
Cullin 1b; Belongs to the cullin family.
    
 0.565
ENSMMOP00000025053
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.565
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.565
ENSMMOP00000023323
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
     
 0.519
ENSMMOP00000003346
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.492
ENSMMOP00000011884
Ring finger protein 7.
    
 0.492
ENSMMOP00000007008
Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.
    
  0.479
Your Current Organism:
Mola mola
NCBI taxonomy Id: 94237
Other names: M. mola, ocean sunfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.