STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSMMOP00000026700TBC1 domain family, member 5. (780 aa)    
Predicted Functional Partners:
ENSMMOP00000019462
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.980
ENSMMOP00000020927
VPS26, retromer complex component A.
   
 
 0.944
ENSMMOP00000020394
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.941
ENSMMOP00000007813
Uncharacterized protein.
   
 
 0.864
ENSMMOP00000018538
VPS26, retromer complex component B.
   
 
 0.864
ENSMMOP00000002441
RAB41, member RAS oncogene family.
   
 
 0.663
ENSMMOP00000008988
RAB6B, member RAS oncogene family a.
   
 
 0.663
ENSMMOP00000021319
RAB6A, member RAS oncogene family.
   
 
 0.663
RAB6B
RAB6B, member RAS oncogene family.
   
 
 0.663
ENSMMOP00000011668
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
    
 
 0.606
Your Current Organism:
Mola mola
NCBI taxonomy Id: 94237
Other names: M. mola, ocean sunfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.