Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
ABLL_1908Ni/Fe-hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (580 aa)    
Predicted Functional Partners:
ABLL_1907
Ni/Fe hydrogenase cytochrome b subunit.
 
 0.999
ABLL_1909
Ni/Fe-hydrogenase small subunit.
 
 0.998
ABLL_1911
Ni/Fe-dependent hydrogenase small subunit.
 
 0.995
ABLL_1906
Ni/Fe hydrogenase expression/formation protein.
 
 
 0.956
hypA
Hydrogenase expression/formation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.917
ABLL_1809
Hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
 
 0.834
ABLL_1810
Hydrogenase expression/formation protein HypC.
 
 
 0.812
ABLL_1811
Hydrogenase expression/formation protein HypB.
 
  
 0.784
ABLL_1806
Hydrogenase expression/formation protein HypE.
 
   
 0.776
ABLL_1842
Transcriptional regulator; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 
 0.740
Your Current Organism:
Arcobacter sp. L
NCBI taxonomy Id: 944547
Other names: A. sp. L
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