| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABLL_0218 | ABLL_0356 | ABLL_0218 | ABLL_0356 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.997 |
| ABLL_0218 | ABLL_0459 | ABLL_0218 | ABLL_0459 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | aminotransferase/L-cysteine desulfhydrase. | 0.929 |
| ABLL_0218 | ABLL_0591 | ABLL_0218 | ABLL_0591 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-adenosylmethionine synthase; Belongs to the AdoMet synthase family. | 0.955 |
| ABLL_0218 | ABLL_2206 | ABLL_0218 | ABLL_2206 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-synthase. | 0.981 |
| ABLL_0218 | ABLL_2207 | ABLL_0218 | ABLL_2207 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-synthase. | 0.978 |
| ABLL_0218 | ABLL_2520 | ABLL_0218 | ABLL_2520 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Threonine deaminase. | 0.899 |
| ABLL_0218 | ABLL_2801 | ABLL_0218 | ABLL_2801 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine sulfhydrylase. | 0.948 |
| ABLL_0218 | luxS | ABLL_0218 | ABLL_0228 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.946 |
| ABLL_0218 | metE | ABLL_0218 | ABLL_2519 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.981 |
| ABLL_0218 | metG | ABLL_0218 | ABLL_1549 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | methionyl-tRNA synthase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.940 |
| ABLL_0356 | ABLL_0218 | ABLL_0356 | ABLL_0218 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.997 |
| ABLL_0356 | ABLL_0591 | ABLL_0356 | ABLL_0591 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | S-adenosylmethionine synthase; Belongs to the AdoMet synthase family. | 0.861 |
| ABLL_0356 | ABLL_2206 | ABLL_0356 | ABLL_2206 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Cystathionine gamma-synthase. | 0.851 |
| ABLL_0356 | ABLL_2207 | ABLL_0356 | ABLL_2207 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Cystathionine gamma-synthase. | 0.851 |
| ABLL_0356 | metE | ABLL_0356 | ABLL_2519 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.923 |
| ABLL_0459 | ABLL_0218 | ABLL_0459 | ABLL_0218 | aminotransferase/L-cysteine desulfhydrase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.929 |
| ABLL_0459 | ABLL_2206 | ABLL_0459 | ABLL_2206 | aminotransferase/L-cysteine desulfhydrase. | Cystathionine gamma-synthase. | 0.946 |
| ABLL_0459 | ABLL_2207 | ABLL_0459 | ABLL_2207 | aminotransferase/L-cysteine desulfhydrase. | Cystathionine gamma-synthase. | 0.932 |
| ABLL_0459 | ABLL_2520 | ABLL_0459 | ABLL_2520 | aminotransferase/L-cysteine desulfhydrase. | Threonine deaminase. | 0.819 |
| ABLL_0459 | ABLL_2801 | ABLL_0459 | ABLL_2801 | aminotransferase/L-cysteine desulfhydrase. | O-acetylhomoserine sulfhydrylase. | 0.936 |