STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clsCardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (488 aa)    
Predicted Functional Partners:
TEH_13740
Putative cation efflux protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
  
    0.792
iscU
Putative iron-sulfur cluster assembly protein IscU.
   
 
 0.749
comEC
Putative competence protein ComEC.
   
 
 0.608
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
       0.528
pgsA
Phosphatidylglycerophosphate synthase; Protein synonym:CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.518
TEH_17270
Hypothetical protein.
  
    0.465
TEH_02310
Putative hydrolase.
  
 
 0.457
mprF
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
  
 0.449
birA
Putative transcriptional regulator/biotin protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.429
TEH_13530
Putative RNA methyltransferase; Belongs to the methyltransferase superfamily.
  
 
   0.415
Your Current Organism:
Tetragenococcus halophilus
NCBI taxonomy Id: 945021
Other names: T. halophilus NBRC 12172, Tetragenococcus halophilus NBRC 12172, Tetragenococcus halophilus str. NBRC 12172, Tetragenococcus halophilus strain NBRC 12172
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