node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
W5A_10739 | W5A_12681 | W5A_10739 | W5A_12681 | Bifunctional protein pyrR; COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | COG0572 Uridine kinase; overlaps another CDS with the same product name. | 0.875 |
W5A_10739 | pyrE | W5A_10739 | W5A_05673 | Bifunctional protein pyrR; COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.785 |
W5A_10739 | pyrF | W5A_10739 | W5A_05063 | Bifunctional protein pyrR; COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | COG0284 Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.956 |
W5A_10739 | pyrH | W5A_10739 | W5A_03684 | Bifunctional protein pyrR; COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.935 |
W5A_10739 | surE | W5A_10739 | W5A_04189 | Bifunctional protein pyrR; COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | 5'(3')-nucleotidase/polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.875 |
W5A_10739 | upp | W5A_10739 | W5A_00610 | Bifunctional protein pyrR; COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | COG0035 Uracil phosphoribosyltransferase. | 0.875 |
W5A_12681 | W5A_10739 | W5A_12681 | W5A_10739 | COG0572 Uridine kinase; overlaps another CDS with the same product name. | Bifunctional protein pyrR; COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase. | 0.875 |
W5A_12681 | pyrE | W5A_12681 | W5A_05673 | COG0572 Uridine kinase; overlaps another CDS with the same product name. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.908 |
W5A_12681 | pyrF | W5A_12681 | W5A_05063 | COG0572 Uridine kinase; overlaps another CDS with the same product name. | COG0284 Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.877 |
W5A_12681 | pyrH | W5A_12681 | W5A_03684 | COG0572 Uridine kinase; overlaps another CDS with the same product name. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.909 |
W5A_12681 | surE | W5A_12681 | W5A_04189 | COG0572 Uridine kinase; overlaps another CDS with the same product name. | 5'(3')-nucleotidase/polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.870 |
W5A_12681 | upp | W5A_12681 | W5A_00610 | COG0572 Uridine kinase; overlaps another CDS with the same product name. | COG0035 Uracil phosphoribosyltransferase. | 0.978 |
frr | ndk | W5A_03679 | W5A_12816 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.801 |
frr | pyrH | W5A_03679 | W5A_03684 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.997 |
frr | rpsB | W5A_03679 | W5A_03694 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.998 |
frr | tsf | W5A_03679 | W5A_03689 | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.980 |
ndk | frr | W5A_12816 | W5A_03679 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.801 |
ndk | pyrH | W5A_12816 | W5A_03684 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.951 |
ndk | rpsB | W5A_12816 | W5A_03694 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.991 |
ndk | tsf | W5A_12816 | W5A_03689 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.497 |