STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (412 aa)    
Predicted Functional Partners:
W5A_02665
COG0527 Aspartokinases.
 
 
 0.977
W5A_06346
COG0527 Aspartokinases.
 
 
 0.976
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
 0.967
W5A_03239
COG0527 Aspartokinases; Belongs to the aspartokinase family.
  
 0.943
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
     
 0.901
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 0.817
W5A_02660
Bifunctional aspartokinase I/homoserine dehydrogenase I; COG2021 Homoserine acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family.
  
 
 0.782
W5A_12741
COG0289 Dihydrodipicolinate reductase; Belongs to the DapB family.
 
 
 0.758
W5A_07090
COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).
    
  0.728
W5A_12056
NAD(P)H dehydrogenase (quinone); COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).
    
  0.728
Your Current Organism:
Imtechella halotolerans
NCBI taxonomy Id: 946077
Other names: Flavobacterium sp. K1, I. halotolerans K1, Imtechella halotolerans K1, Imtechella halotolerans str. K1, Imtechella halotolerans strain K1
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