STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5A_13375colD-shock DNA-binding protein family; COG1278 Cold shock proteins. (144 aa)    
Predicted Functional Partners:
W5A_13370
Dead/deah box helicase domain protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.
   
  0.819
W5A_13365
COG0724 RNA-binding proteins (RRM domain).
   
  0.798
W5A_13380
DNA-binding cold-shock protein; COG1278 Cold shock proteins.
       0.708
W5A_06660
Hypothetical protein.
  
 
 0.645
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
   0.603
W5A_03539
Peptidase M56 BlaR1.
  
     0.582
rpsQ
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
   0.575
rplP
50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
   
   0.570
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
   0.569
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
   0.567
Your Current Organism:
Imtechella halotolerans
NCBI taxonomy Id: 946077
Other names: Flavobacterium sp. K1, I. halotolerans K1, Imtechella halotolerans K1, Imtechella halotolerans str. K1, Imtechella halotolerans strain K1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.