node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RvY_04533-1 | RvY_04640-1 | A0A1D1UVH6 | A0A1D1UYZ8 | CNNM transmembrane domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.707 |
RvY_04533-1 | RvY_05002-1 | A0A1D1UVH6 | A0A1D1UWM9 | CNNM transmembrane domain-containing protein. | Uncharacterized protein. | 0.670 |
RvY_04533-1 | RvY_07075-1 | A0A1D1UVH6 | A0A1D1V9F3 | CNNM transmembrane domain-containing protein. | Pribosyltran domain-containing protein. | 0.685 |
RvY_04533-1 | RvY_08158-1 | A0A1D1UVH6 | A0A1D1V4U6 | CNNM transmembrane domain-containing protein. | Pribosyltran domain-containing protein. | 0.699 |
RvY_04533-1 | RvY_11358-1 | A0A1D1UVH6 | A0A1D1VFV8 | CNNM transmembrane domain-containing protein. | Uncharacterized protein. | 0.779 |
RvY_04533-1 | RvY_12970-1 | A0A1D1UVH6 | A0A1D1VUY4 | CNNM transmembrane domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.677 |
RvY_04533-1 | RvY_14574-1 | A0A1D1UVH6 | A0A1D1VRR8 | CNNM transmembrane domain-containing protein. | TYR_PHOSPHATASE_2 domain-containing protein. | 0.496 |
RvY_04533-1 | RvY_15566 | A0A1D1UVH6 | A0A1D1VVD3 | CNNM transmembrane domain-containing protein. | MGS domain-containing protein. | 0.668 |
RvY_04533-1 | RvY_15566-2 | A0A1D1UVH6 | A0A1D1W3B4 | CNNM transmembrane domain-containing protein. | MGS domain-containing protein. | 0.668 |
RvY_04533-1 | RvY_17755-1 | A0A1D1UVH6 | A0A1D1W6Y8 | CNNM transmembrane domain-containing protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.720 |
RvY_04640-1 | RvY_04533-1 | A0A1D1UYZ8 | A0A1D1UVH6 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | CNNM transmembrane domain-containing protein. | 0.707 |
RvY_04640-1 | RvY_05002-1 | A0A1D1UYZ8 | A0A1D1UWM9 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Uncharacterized protein. | 0.957 |
RvY_04640-1 | RvY_07075-1 | A0A1D1UYZ8 | A0A1D1V9F3 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Pribosyltran domain-containing protein. | 0.940 |
RvY_04640-1 | RvY_08158-1 | A0A1D1UYZ8 | A0A1D1V4U6 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Pribosyltran domain-containing protein. | 0.924 |
RvY_04640-1 | RvY_11358-1 | A0A1D1UYZ8 | A0A1D1VFV8 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Uncharacterized protein. | 0.999 |
RvY_04640-1 | RvY_12970-1 | A0A1D1UYZ8 | A0A1D1VUY4 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.944 |
RvY_04640-1 | RvY_15566 | A0A1D1UYZ8 | A0A1D1VVD3 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | MGS domain-containing protein. | 0.964 |
RvY_04640-1 | RvY_15566-2 | A0A1D1UYZ8 | A0A1D1W3B4 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | MGS domain-containing protein. | 0.964 |
RvY_04640-1 | RvY_17755-1 | A0A1D1UYZ8 | A0A1D1W6Y8 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.992 |
RvY_05002-1 | RvY_04533-1 | A0A1D1UWM9 | A0A1D1UVH6 | Uncharacterized protein. | CNNM transmembrane domain-containing protein. | 0.670 |