STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RvY_06051-1Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1031 aa)    
Predicted Functional Partners:
RvY_15903-1
Uncharacterized protein.
    
 0.999
RvY_09161-1
Uncharacterized protein.
    
 0.992
RvY_05998-1
TPR_REGION domain-containing protein.
    
 0.981
RvY_15454-1
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.737
RvY_07938-1
WD_REPEATS_REGION domain-containing protein.
    
 
0.728
RvY_18357-1
WD_REPEATS_REGION domain-containing protein.
    
 
0.728
RvY_01498-1
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.723
RvY_14271-1
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.723
RvY_15413-1
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.723
RvY_15412-1
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.723
Your Current Organism:
Ramazzottius varieornatus
NCBI taxonomy Id: 947166
Other names: R. varieornatus
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