STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RvY_10213-1Rad51d. (401 aa)    
Predicted Functional Partners:
RvY_05095-1
DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.
  
0.995
RvY_17812-1
Rad51b.
   
 0.994
RvY_16415-1
BRCT domain-containing protein.
   
 0.990
RvY_08252-1
Uncharacterized protein.
   
 0.989
RvY_09674-1
Rad51c XRCC2.
   
 0.985
RvY_18611-1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
  
 0.949
RvY_07369-1
Uncharacterized protein.
  
 0.934
RvY_06935-1
Uncharacterized protein.
  
 0.923
RvY_10238-1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.923
RvY_02973-1
Rad50.
  
 0.915
Your Current Organism:
Ramazzottius varieornatus
NCBI taxonomy Id: 947166
Other names: R. varieornatus
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