STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RvY_15881-1PABS domain-containing protein. (349 aa)    
Predicted Functional Partners:
RvY_05331-1
Uncharacterized protein.
   
 0.972
RvY_08551-1
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
  
 
 0.953
RvY_18181-1
S-adenosylmethionine decarboxylase proenzyme.
    
 0.947
RvY_18477-1
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
 0.873
RvY_11890-1
Uncharacterized protein.
    
 0.867
RvY_12826-1
Probable lysine-specific histone demethylase 1; Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3.
   
 0.853
RvY_05468-1
Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 0.847
RvY_06207-1
Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 0.847
RvY_02076
Uncharacterized protein.
  
 
 0.823
RvY_02076-1
Uncharacterized protein.
  
 
 0.823
Your Current Organism:
Ramazzottius varieornatus
NCBI taxonomy Id: 947166
Other names: R. varieornatus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.