STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RvY_17011-1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (530 aa)    
Predicted Functional Partners:
RvY_14372-1
Homeobox domain-containing protein.
   
 
 0.983
RvY_10603-1
Homeobox domain-containing protein.
   
 
 0.931
RvY_09290-1
SIX1_SD domain-containing protein.
   
 
 0.886
RvY_15454-1
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.609
RvY_15343-1
Uncharacterized protein.
     
 0.590
RvY_03565-1
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
      
 0.553
RvY_00201-1
Uncharacterized protein.
      
 0.552
RvY_05958-1
Histone H2A; Belongs to the histone H2A family.
    
 0.552
RvY_06057-1
Histone H2A; Belongs to the histone H2A family.
    
 0.552
RvY_10340-1
Histone H2A; Belongs to the histone H2A family.
    
 0.552
Your Current Organism:
Ramazzottius varieornatus
NCBI taxonomy Id: 947166
Other names: R. varieornatus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.