STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RvY_17201-1Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (679 aa)    
Predicted Functional Partners:
RvY_05319-1
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
RvY_06912-1
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.999
RvY_05257-1
Dihydrolipoyl dehydrogenase.
 0.999
RvY_06203-1
Protein-serine/threonine kinase.
    
 0.987
RvY_08758-1
Transket_pyr domain-containing protein.
  
 0.979
RvY_09532-1
Lipoyl-binding domain-containing protein.
  
0.979
RvY_16940-1
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
 
 0.978
RvY_09961-1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.972
RvY_03861-1
Transket_pyr domain-containing protein.
 0.970
RvY_16160-1
ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
  
 0.958
Your Current Organism:
Ramazzottius varieornatus
NCBI taxonomy Id: 947166
Other names: R. varieornatus
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