STRINGSTRING
STAT3 protein (Callithrix jacchus) - STRING interaction network
"STAT3" - Signal transducer and activator of transcription 3 (acute-phase response factor) in Callithrix jacchus
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
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[Homology]
Score
STAT3Signal transducer and activator of transcription 3 (acute-phase response factor) (772 aa)    
Predicted Functional Partners:
JAK2
Janus kinase 2 (1132 aa)
     
 
  0.976
EGFR
Receptor protein-tyrosine kinase; Epidermal growth factor receptor (1210 aa)
       
 
  0.957
IL6
Uncharacterized protein; Interleukin 6 (249 aa)
       
 
  0.956
IL10
Interleukin-10; Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells (178 aa)
       
 
  0.924
SOCS3
Suppressor of cytokine signaling 3 (225 aa)
     
 
  0.923
JAK1
Janus kinase 1 (1156 aa)
     
 
  0.918
AKT1
V-akt murine thymoma viral oncogene homolog 1 (465 aa)
       
 
  0.907
JAK3
Uncharacterized protein; Janus kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family (273 aa)
     
 
  0.902
LEP
Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal met [...] (167 aa)
           
  0.893
SRC
Tyrosine-protein kinase; SRC proto-oncogene, non-receptor tyrosine kinase (542 aa)
     
 
  0.887
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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