Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLBKlotho beta. (1045 aa)    
Predicted Functional Partners:
FGFR1
Fibroblast growth factor receptor.
    
 0.998
FGFR4
Fibroblast growth factor receptor.
    
 0.970
FGF23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
    
 0.952
FGF21
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.930
FGF19
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.926
FGFR2
Fibroblast growth factor receptor.
    
 0.810
FGFR3
Fibroblast growth factor receptor.
    
 0.766
FRS2
Fibroblast growth factor receptor substrate 2.
     
 0.642
HS6ST1
Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
      
 0.620
ANOS1
Anosmin 1.
      
 0.620
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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