STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OTUD7BOTU domain-containing protein 7B. (843 aa)    
Predicted Functional Partners:
ENSCJAP00000059313
Uncharacterized protein.
   
 0.856
UBC
Uncharacterized protein.
   
 0.812
UBA52
Ubiquitin-like domain-containing protein.
    
  0.811
UBXN7
UBX domain-containing protein 7.
   
 
 0.768
LOC100411827
Ubiquitin-like domain-containing protein.
    
  0.733
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.646
WIPI1
WD repeat domain phosphoinositide-interacting protein 1.
      
 0.640
TNF
Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]
   
 0.621
USP45
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
 
 0.598
USP48
Ubiquitin specific peptidase 48; Belongs to the peptidase C19 family.
    
 
 0.598
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.