Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABCG5ATP binding cassette subfamily G member 5. (651 aa)    
Predicted Functional Partners:
ABCG8
ATP binding cassette subfamily G member 8.
  
0.999
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
   
 
 0.886
CYP7A1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 
 0.830
ABCG1
ATP-binding cassette sub-family G member 1 isoform 4.
   
0.827
NR1H4
Nuclear receptor subfamily 1 group H member 4.
   
 0.796
ABCG2
ATP-binding cassette sub-family G member 2 isoform 1.
   
 0.775
ABCG4
ATP-binding cassette sub-family G member 4.
   
 0.775
HMGCR
3-hydroxy-3-methylglutaryl coenzyme A reductase.
      
 0.716
XPR1
Xenotropic and polytropic retrovirus receptor 1.
    
 
 0.706
SREBF2
Sterol regulatory element binding transcription factor 2.
    
 
 0.694
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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