H9KVN3_CALJA protein (Callithrix jacchus) - STRING interaction network

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Score

H9KVN3_CALJA

Ig-like domain-containing protein. (326 aa)

Predicted Functional Partners:

CD83

0.794

CD86

0.665

CD80

0.642

B2M

0.620

RPA2

0.620

ENSCJAP00000073535

0.620

CD4

0.579

IL4

0.576

CD40

0.548

IFNG

0.534

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B2M	CD4	ENSCJAP00000048032	ENSCJAP00000043597	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Ig-like domain-containing protein.	0.661
B2M	CD80	ENSCJAP00000048032	ENSCJAP00000078516	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Uncharacterized protein.	0.526
B2M	H9KVN3_CALJA	ENSCJAP00000048032	ENSCJAP00000001553	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Ig-like domain-containing protein.	0.620
B2M	IFNG	ENSCJAP00000048032	ENSCJAP00000056963	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	0.613
B2M	IL4	ENSCJAP00000048032	ENSCJAP00000024044	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	0.400
CD4	B2M	ENSCJAP00000043597	ENSCJAP00000048032	Ig-like domain-containing protein.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.661
CD4	CD40	ENSCJAP00000043597	ENSCJAP00000054885	Ig-like domain-containing protein.	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	0.907
CD4	CD80	ENSCJAP00000043597	ENSCJAP00000078516	Ig-like domain-containing protein.	Uncharacterized protein.	0.930
CD4	CD83	ENSCJAP00000043597	ENSCJAP00000060174	Ig-like domain-containing protein.	CD83 antigen isoform a.	0.693
CD4	CD86	ENSCJAP00000043597	ENSCJAP00000015187	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.933
CD4	H9KVN3_CALJA	ENSCJAP00000043597	ENSCJAP00000001553	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.579
CD4	IFNG	ENSCJAP00000043597	ENSCJAP00000056963	Ig-like domain-containing protein.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	0.960
CD4	IL4	ENSCJAP00000043597	ENSCJAP00000024044	Ig-like domain-containing protein.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	0.937
CD40	CD4	ENSCJAP00000054885	ENSCJAP00000043597	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	Ig-like domain-containing protein.	0.907
CD40	CD80	ENSCJAP00000054885	ENSCJAP00000078516	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	Uncharacterized protein.	0.967
CD40	CD83	ENSCJAP00000054885	ENSCJAP00000060174	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	CD83 antigen isoform a.	0.864
CD40	CD86	ENSCJAP00000054885	ENSCJAP00000015187	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	Ig-like domain-containing protein.	0.965
CD40	H9KVN3_CALJA	ENSCJAP00000054885	ENSCJAP00000001553	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	Ig-like domain-containing protein.	0.548
CD40	IFNG	ENSCJAP00000054885	ENSCJAP00000056963	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	0.917
CD40	IL4	ENSCJAP00000054885	ENSCJAP00000024044	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	0.842