Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGMOAlkylglycerol monooxygenase; Belongs to the sterol desaturase family. (445 aa)    
Predicted Functional Partners:
ALDH3A2
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
  
 0.718
FA2H
Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]
      
 0.689
DCTD
dCMP deaminase.
      
 0.670
MEOX2
Mesenchyme homeobox 2.
 
    
 0.625
EDA
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
      
 0.580
CPZ
Carboxypeptidase Z.
      
 0.574
SORBS3
Vinexin isoform 1.
      
 0.571
ARHGAP6
Rho GTPase activating protein 6.
    
 
 0.570
PNMT
Phenylethanolamine N-methyltransferase.
      
 0.562
CRPPA
Isoprenoid synthase domain-containing protein isoform a.
      
 0.523
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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