STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MEOX2Mesenchyme homeobox 2. (303 aa)    
Predicted Functional Partners:
TAPT1
Transmembrane anterior posterior transformation 1.
      
 0.687
PAX9
Paired box protein Pax-9; Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs.
    
 
 0.667
INSR
Tyrosine-protein kinase receptor.
    
 
 0.649
AGMO
Alkylglycerol monooxygenase; Belongs to the sterol desaturase family.
 
    
 0.626
MEOX1
Mesenchyme homeobox 1.
   
 
0.598
DEAF1
DEAF1 transcription factor.
    
 
 0.595
OSR1
Odd-skipped related transcription factor 1.
   
 
 0.556
LEP
Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]
      
 0.555
TCF15
Transcription factor 15.
   
 
 0.549
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 
 0.546
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (18%) [HD]