STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCKTyrosine-protein kinase. (539 aa)    
Predicted Functional Partners:
CD4
Ig-like domain-containing protein.
   
 0.990
ZAP70
Zeta chain of T cell receptor associated protein kinase 70.
  
0.970
PTPRC
Protein tyrosine phosphatase receptor type C.
   
 0.938
CD8A
CD8a molecule.
   
 
 0.927
CD247
CD247 molecule.
   
 0.927
SYK
Uncharacterized protein.
  
0.909
LCP2
Lymphocyte cytosolic protein 2.
   
 0.885
FYN
Tyrosine-protein kinase.
  
0.871
LAT
Linker for activation of T cells.
   
 0.863
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.844
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.