STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFAP1Actin filament associated protein 1. (830 aa)    
Predicted Functional Partners:
GMDS
GDP-mannose 4,6 dehydratase isoform 1.
      
 0.821
SIX5
SIX homeobox 5.
      
 0.770
SRC
Tyrosine-protein kinase.
    
 
 0.693
NIPSNAP2
Protein NipSnap homolog 2 isoform 1.
      
 0.686
ITIH1
Inter-alpha-trypsin inhibitor heavy chain 1.
    
 
 0.636
SIX6
SIX homeobox 6.
      
 0.570
PSPH
Phosphoserine phosphatase.
      
 0.567
TMCO1
Transmembrane and coiled-coil domains 1.
      
 0.535
CAV2
Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...]
      
 0.520
SH3TC1
SH3 domain and tetratricopeptide repeats 1.
      
 0.497
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.