STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AP4E1Adaptor related protein complex 4 subunit epsilon 1. (1142 aa)    
Predicted Functional Partners:
AP4B1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
   
 0.995
AP4S1-2
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.987
ENSCJAP00000067149
Uncharacterized protein.
   
 0.971
ENSCJAP00000069046
J domain-containing protein.
   
 0.971
AP4M1
AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]
   
 0.957
ITSN2
Intersectin 2.
    
 0.941
ENSCJAP00000078263
Uncharacterized protein.
    
 0.941
AP4S1
Adaptor related protein complex 4 subunit sigma 1.
    
 0.921
AP2S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.903
AP2B1
AP complex subunit beta.
   
0.886
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.