STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (469 aa)    
Predicted Functional Partners:
IRAK1
Interleukin-1 receptor-associated kinase 1 isoform 1 (Predicted).
    
 0.942
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.867
IRAK4
Interleukin-1 receptor-associated kinase 4 isoform a.
    
 0.859
ENSCJAP00000068236
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.756
UBE2V1
TMEM189_B_dmain domain-containing protein.
    
 0.756
IRAK2
Interleukin 1 receptor associated kinase 2.
    
 0.748
RIPK1
Receptor-interacting serine/threonine-protein kinase 1.
    
 0.646
RIPK3
Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily.
    
 0.604
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    
 0.550
IQCC
IQ motif containing C.
      
 0.531
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.