STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (627 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
    
 0.953
XPC
XPC complex subunit, DNA damage recognition and repair factor.
   
 0.832
HELLS
Helicase, lymphoid specific.
   
 0.830
CUL4A
Cullin 4A; Belongs to the cullin family.
    
 0.794
CUL4B
Cullin 4B; Belongs to the cullin family.
    
 0.794
COPS2
COP9 signalosome complex subunit 2 isoform 2.
    
 0.749
COPS8
PCI domain-containing protein.
    
 0.747
COPS4
COP9 signalosome subunit 4.
    
 0.744
GPRIN1
G protein regulated inducer of neurite outgrowth 1.
    
 
 0.730
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.723
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.