STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLXNB2Plexin-B2. (1839 aa)    
Predicted Functional Partners:
SEMA4D
Semaphorin-4D isoform 1; Belongs to the semaphorin family.
    
 0.999
RND1
Rho-related GTP-binding protein Rho6.
    
 0.992
SEMA4C
Semaphorin-4C; Belongs to the semaphorin family.
   
0.983
SEMA4F
Semaphorin-4F isoform 1; Belongs to the semaphorin family.
   
 0.978
ARHGEF12
Rho guanine nucleotide exchange factor 12.
    
 0.977
RRAS
Ras-related protein R-Ras.
    
 0.975
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
    
0.974
SEMA4A
Semaphorin-4A isoform 1; Belongs to the semaphorin family.
    
0.972
SEMA4B
Semaphorin 4B; Belongs to the semaphorin family.
    
0.969
RAC3
Ras-related C3 botulinum toxin substrate 3.
   
 0.950
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (18%) [HD]