node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARHGEF12 | MET | ENSCJAP00000026285 | ENSCJAP00000009442 | Rho guanine nucleotide exchange factor 12. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.494 |
ARHGEF12 | PLXNB2 | ENSCJAP00000026285 | ENSCJAP00000005956 | Rho guanine nucleotide exchange factor 12. | Plexin-B2. | 0.977 |
ARHGEF12 | RAC3 | ENSCJAP00000026285 | ENSCJAP00000033666 | Rho guanine nucleotide exchange factor 12. | Ras-related C3 botulinum toxin substrate 3. | 0.438 |
ARHGEF12 | RND1 | ENSCJAP00000026285 | ENSCJAP00000074772 | Rho guanine nucleotide exchange factor 12. | Rho-related GTP-binding protein Rho6. | 0.683 |
ARHGEF12 | RRAS | ENSCJAP00000026285 | ENSCJAP00000006562 | Rho guanine nucleotide exchange factor 12. | Ras-related protein R-Ras. | 0.927 |
ARHGEF12 | SEMA4D | ENSCJAP00000026285 | ENSCJAP00000048964 | Rho guanine nucleotide exchange factor 12. | Semaphorin-4D isoform 1; Belongs to the semaphorin family. | 0.593 |
MET | ARHGEF12 | ENSCJAP00000009442 | ENSCJAP00000026285 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Rho guanine nucleotide exchange factor 12. | 0.494 |
MET | PLXNB2 | ENSCJAP00000009442 | ENSCJAP00000005956 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Plexin-B2. | 0.974 |
MET | RAC3 | ENSCJAP00000009442 | ENSCJAP00000033666 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Ras-related C3 botulinum toxin substrate 3. | 0.604 |
MET | RND1 | ENSCJAP00000009442 | ENSCJAP00000074772 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Rho-related GTP-binding protein Rho6. | 0.690 |
MET | RRAS | ENSCJAP00000009442 | ENSCJAP00000006562 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Ras-related protein R-Ras. | 0.605 |
MET | SEMA4A | ENSCJAP00000009442 | ENSCJAP00000010266 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Semaphorin-4A isoform 1; Belongs to the semaphorin family. | 0.684 |
MET | SEMA4B | ENSCJAP00000009442 | ENSCJAP00000017408 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Semaphorin 4B; Belongs to the semaphorin family. | 0.684 |
MET | SEMA4C | ENSCJAP00000009442 | ENSCJAP00000014858 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Semaphorin-4C; Belongs to the semaphorin family. | 0.684 |
MET | SEMA4D | ENSCJAP00000009442 | ENSCJAP00000048964 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Semaphorin-4D isoform 1; Belongs to the semaphorin family. | 0.782 |
MET | SEMA4F | ENSCJAP00000009442 | ENSCJAP00000066628 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Semaphorin-4F isoform 1; Belongs to the semaphorin family. | 0.684 |
PLXNB2 | ARHGEF12 | ENSCJAP00000005956 | ENSCJAP00000026285 | Plexin-B2. | Rho guanine nucleotide exchange factor 12. | 0.977 |
PLXNB2 | MET | ENSCJAP00000005956 | ENSCJAP00000009442 | Plexin-B2. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.974 |
PLXNB2 | RAC3 | ENSCJAP00000005956 | ENSCJAP00000033666 | Plexin-B2. | Ras-related C3 botulinum toxin substrate 3. | 0.950 |
PLXNB2 | RND1 | ENSCJAP00000005956 | ENSCJAP00000074772 | Plexin-B2. | Rho-related GTP-binding protein Rho6. | 0.992 |