STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSRGlutathione reductase, mitochondrial; Maintains high levels of reduced glutathione in the cytosol. (522 aa)    
Predicted Functional Partners:
GPX2
Glutathione peroxidase 2.
  
 0.985
GPX6
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 0.982
GPX5
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 0.982
GPX7
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 0.982
GPX3
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 0.978
GPX8
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
  
 0.978
GPX4
Phospholipid hydroperoxide glutathione peroxidase; Essential antioxidant peroxidase that directly reduces phospholipid hydroperoxide even if they are incorporated in membranes and lipoproteins (By similarity). Can also reduce fatty acid hydroperoxide, cholesterol hydroperoxide and thymine hydroperoxide (By similarity). Plays a key role in protecting cells from oxidative damage by preventing membrane lipid peroxidation. Required to prevent cells from ferroptosis, a non-apoptotic cell death resulting from an iron- dependent accumulation of lipid reactive oxygen species. The presence of s [...]
  
 0.973
GSS
Glutathione synthetase.
    
 0.964
PRDX6-2
Thioredoxin domain-containing protein.
   
 0.948
GSTO1
Glutathione S-transferase omega-1 isoform 1.
   
 
 0.937
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.