STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAN2B2Alpha-mannosidase. (1175 aa)    
Predicted Functional Partners:
ENSCJAP00000068949
Alpha-mann_mid domain-containing protein.
     
 0.923
MAN2B1
Alpha-mannosidase.
  
  
0.908
MOGS
Mannosyl-oligosaccharide glucosidase isoform 1.
   
  
 0.833
SLC35C1
GDP-fucose transporter 1 isoform a.
      
 0.817
ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
      
 0.760
MAN1B1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
  
 0.666
ZPBP2
Zona pellucida binding protein 2.
      
 0.644
CD46
Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity (By similarity).
      
 0.641
ALG13
ALG13 UDP-N-acetylglucosaminyltransferase subunit.
      
 0.625
ALG6
Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family.
      
 0.587
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.